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time goes on, it becomes more evident that the most important feature of the immune system is not that of defending the body from external aggressions, but to impede useless reactions, that is, to actively tolerate external agents. Immune tolerance enables any human being to come into contact with foreign substances (food or respiratory that they may be) without being harmed The mysteries behind immune tolerance are clearer today thanks to a study performed by researches form the University of Trieste and published online at the end of December 2007 (Longo G. et al. J Allergy Clin Immunol 2007 Dec 22 [Epub ahead of print]).
Several days ago, an important article written by Paola Magni that discussed the work of the researchers from Trieste was published on Lifegate. The scientists were able to induce tolerance to cow's milk in children who had serious allergic reactions to the milk itself.
In this way they were able to help sick children to resume eating milk or its by-products in a way that trained their bodies to tolerate the substance. By way of the introduction of minimum quantities of milk that were gradually increased, these children with grave allergic reactions like anaphylactic shock, were able to resume eating milk and incorporate it into their diets.
Other researchers have had similar experiences in the same area; in Italy, for example, Patriarca followed by Speciani, studied hypo-sensitization to nickel , in order to allow patients with nickel dermatitis to eat freely. In the United States, Sampson was able to obtain tolerance in patients who were allergic to peanuts by using small quantities of a similar substance (like soy) . The SMA center in Milan, as part of an observational study sponsored by The Lombardy Region, is concluding interesting studies on low dosage hypo-sensitization to Candida. for those persons who suffer from Candida or recurring cystitis.
Therefore, important therapeutic instruments for helping to restore immune tolerance are already available and can be used on a broad scale and in a safe manner. These studies confirm the risk and danger involved in useless elimination diets that no one should ever implement. Some doubts are even arising for problems such as celiac disease.
Practical science continues to make advances and the development of the fundamental themes of immunology (why do we become allergic?) becomes urgent. Unfortunately, however, the majority of specialists remain tied to obsolete ideas, asking their patients to avoid foods or allergenic substances, instead of working on a new model that science is proving more and more to be valid and safe
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