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Today food intolerances and the connections between food and inflammation in general are an undeniable scientific reality supported by important studies published in authoritative international journals. In particular we would like to point out the following works to all therapists who follow our website:
— Sampson H. Update on food allergy. J Allergy Clin Immunol 2004 May;113(5):805-19; quiz 820, an article in which Sampson anticipates the existence of delayed food allergies, immunological phenomena related to the repetition over consecutive days of an allergic stimulus on the intestinal cells. Therefore food intolerances could be defined as delayed food allergies, different from IgE-modulated immediate allergies.
— Finkelman FD. J Allergy Clin Immunol 2007;120:506-15, an article that signals the existence of two different allergy routes: the classic one (IgE and mast cells) and an alternative one (Granulocytes, PAF, IgG) which however cause the same effects. Thus, any previous diagnosis of allergy that was performed without considering the alternative route can be considered incomplete
— Brandt EB et al, J Allergy Clin Immunol 2006 Aug;118(2):420-7, an article that confirms the fact that the introduction of a non-tolerated food, in the presence of mites or molds, can give rise to symptoms resembling those of respiratory allergies. These symptoms, which may persist for more than 10 days, can even occur in persons who don't have IgE's for mites and molds. This means that many patients with respiratory pathologies may simply be food intolerant.
— Karatay S. et al Rheumatol (Oxford)2004 Nov;43(11):1429-33. Epub 2004 Aug, the article states that a load of non-tolerated food can cause the reactivation of arthritic forms in subjects who are in remission from rheumatoid arthritis. This occurs in much the same way as for the respiratory forms described by Brandt. This means that a doctor must always evaluate a patient's joint pains in a new way, taking into consideration food reactivity as well as that of the adipokines as a cause.
— Buchanan AD et al, J Allergy Clin Immunol 2007 Jan;119(1):199-205. Epub 2006 Oct 27, an important article that sanctioned the possibility of using oral hyposensitization for an effective cure of allergy and food intolerance. When used therapeutically, these low dosage preparations can help patients regain tolerance, or, in the case of respiratory allergens, specific antigen tolerance (mites, molds, pollens).
— Longo G. et al. J Allergy Clin Immunol 2008 Feb;121(2):343-7 Epub 2007 Dec 22. In this article a group of Italian researchers recently documented the possibility of recreating tolerance by way of oral hyposensitization with low doses of the non-tolerated food, even in the case of severe food allergies. In particular, the researchers followed tolerance induction treatment in persons who were allergic to milk. As a result, the subjects were able to resume regular use of the food in a relatively short period of time.
Today, the theme of tolerance reeducation, whether by means of oral hyposenstization, or through the use of dietary and nutritional techniques, is of considerable scientific relevance: the following are several of the most important articles that discuss this topic.
— Frossard CP et al, J Allergy Clin Immunol 2004;113:958-964. This is one of the most important articles dealing with tolerance induction. By using experimental models of food allergies, Frossard was able to induce tolerance recovery by liberally giving the patient a low concentration of allergen. In this same study, a severe betalactoglobulin allergy was cured by giving the patient water that was "tainted" with betalactoglobulin in a concentration of 0,8 mg/mL (more or less equal to a bit of milk in a small cup of espresso coffee).
— Pons L et al., J Allergy Clin Immunol 2004;114(4):915-21. In this study, Sampson's group was able to cure a sever soy allergy thanks to a vaccination with a “similar” substance (that is, with a lesser soy determinant). This supports the frequent clinical practice of using hyposensitizing treatment based on similar substances, and not necessarily equivalent ones. For example, a hypersensitivity to Candida can often be treated with a low concentration of a different fungus or yeast.
Even in the area of celiac disease, many previous convictions are now subject to review. Especially with regard to cases of transitory celiac disease, several studies clearly discuss the possibilities for its cure.
— Patriarca G et al, Int J Immunopathol Pharmacol 2005 Oct-Dec;18(4):709-14. This article discusses how, thanks to a controlled use of gluten by way of a gradual and progressive scheme, a woman suffering from celiac disease was able to safely return to a normal and varied diet.
This study on celiac disease, together with others that can be found on Eurosalus, leave open the possibility for resuming a varied and liberal diet at least for some subgroups of patients with gluten intolerance.
Eurosalus hosts a FORUM FOR PROFESSIONALS for reserved discussion of these themes. Since food intolerances, diet formulation, hyposensitizing therapy, insulin sensitivity control and other themes related to the GIFT diet and nutritional planning for delayed food allergies can be addressed in the FORUM, any professional can discuss these themes and seek help or advice if needed.
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